Pushing the Boundaries of Regenerative Science

In this study, we showed that SPSCs and SPSC-derived exosomes show great potential in chronic nerve pain conditions.

In this study, we proved that a controlled palmar cooling under vacuum conditions results in an increase in ciculating stem cells in peripheral blood.

• potential therapeutic effects in the future are discussed.

In this study, we investigate the cell population we discovered and named SPSC last year, and demonstrate that they behave very similar to embryonic stem cells in cell culture.

• 150 - 250 million stem cells from six blood collection tubes
• Pluripotent according to four antibody markers
• Minimally invasive
• No laboratory manipulation

Our most groundbreaking study to date. A preclinical study, in which we present a new and unique way to extract pluripotent stem cells from blood.

• 150 - 250 million stem cells from six blood collection tubes
• Pluripotent according to four antibody markers
• Minimally invasive
• No laboratory manipulation

Amniotic-Derived Exosomes in Clinical Practice: Safety and Outcomes in 608 Patients

• 608 patients over a two-year period
• Positive effects in a clear majority of the treated conditions
• Minimal, self-resolving, side effect

Amniotic Derived Exosomes with Platelet Rich Fibrin Combined in the Treatment of Hip and Knee Osteoarthritis: A Retrospective 1-Year Follow-Up Study

• 114 patients with 1-year follow-up
• Exosome treatment for knees and hips
• Significantly lowered WOMAC score.
• Increased cartilage on ultrasound before- and after pictures.

Platelet Rich Fibrin Combined with Hyaluronic Acid in the Treatment of Meniscal Injuries: A Retrospective 1-Year Follow-Up Study

• 78 patients with 1-year follow-up
• Reduced pain according to NRS pain scores
• Positive effect shown through sonographic imaging
• Long-lasting effect
• PRF combined with hyaluronic acid

Hydrogel alone or in Combination with Regenerative Interventions for Knee Osteoarthritis, A Case Series

• Case series with promising results
• Reduced pain according to NRS pain scores and WOMAC
• A "membrane" effect where the hydrogel acts as a scaffold for cells was shown.

Platelet-Rich Fibrin in Combination with Heat-Coagulated Albumin Gel as Treatment for Lateral Epicondylitis: A Retrospective 1-Year Follow-Up Study

• 528 patients with 1-year follow-up
• Platelet injection combined with albumin gel
• Long-lasting effect indicated by follow-up data
• Reduced pain according to NRS pain scores

Exosome-Based Therapy for Osteoarthritis: A Systematic Review

• Systematic review
• 27 research articles
• Exosomes demonstrate strong anti-inflammatory and regenerative properties

Stromal Vascular Fraction with Platelet-Rich Fibrin for Osteoarthritis Management in Knee and Hip Osteoarthritis: A Retrospective 2-Year Follow-Up Study

• 104 patients with 2-year follow-up
• Stem cells and Platelet injections combined with heat-coagulated albumin gel
• Long-lasting effect indicated by follow-up data
• Reduced pain according to NRS pain scores
• Increased joint space on radiographic before- and after pictures.

Amniotic Derived Exosomes in the Treatment of Degenerative Bone- and Cartilage Disease: A Case Series

• Case series of 3 male patients with chronic, treatment-resistant pain
• Significant reduction in pain and improved joint function after a single exosome injection
• Suggests strong regenerative potential when combined with PRF and SVF therapies

Treatment of Osgood-Schlatter Disease in an Adolescent Athlete with Liquid Platelet-Rich Fibrin and Heat-Coagulated Albumin Gel: A Case Report

• Case report of a 13-year-old boy with 3-year chronic Osgood-Schlatter disease
• Complete remission of ossification and pain after three injections of PRF and ALB-PRF
• Returned to elite-level sports within 2 months; no relapse after 2 years

Treatment of a Fractured Humerus and Partially Torn Supraspinatus Tendon in a Professional Boxer with Liquid Platelet-Rich Fibrin and Heat-Coagulated Albumin Gel: A Case Report

• 33-year-old professional boxer with delayed humerus fracture and rotator cuff tear
• Full clinical recovery and radiographic healing achieved within 1 month using PRF and ALB-PRF
• Returned to professional boxing in 3 months, no relapse after 1 year

Regenerative Medicine Treatment Using Stromal Vascular Fraction (SVF) and Platelet-Rich Fibrin (PRF)

• Case series across 7 patients with osteoarthritis in joints including knee, hip, ankle, shoulder, hand, and foot
• All patients treated with SVF and PRF injections combined with structured rehabilitation; notable improvements in pain, mobility, and joint space on imaging
• SVF (adipose-derived stem cells) and PRF used as a minimally invasive alternative to surgery—patients returned to daily activities and sports, some after years of inactivity